D. Madej1, A. Sobczak1,2
1) Medical University of Silesia, School of Pharmacy, Department of General and Inorganic Chemistry, Sosnowiec, PL; 2) Institute of Occupational Medicine and Environmental Health, Department of Chemical Hazards and Genetic Toxicology, Sosnowiec, PL


The present review of the scientific literature relates to the content of toxic compounds in the aerosol generated during electronic cigarettes use. An electronic cigarette, also known as an e-cigarette or electronic nicotine delivery system, has become a popular alternative to a conventional cigarette within a few years of its invention. Initially, it was advertised as being a safer form of nicotine delivery to an organism. That reasoning was dictated by the way these devices operate. In electronic cigarettes occur evaporation process of the e-liquid containing nicotine. E-liquid mainly consists of propylene glycol, glycerin, nicotine, and flavours. With the exception of nicotine, the remaining substances are considered safe. However, as the research results show, the chemical composition of the generated aerosol differs from the composition of e-liquids. This is due to the partial conversion of the e-liquid components at the aerosol generation temperature. In this way, toxic substances are formed, also those that are not present in tobacco smoke. This paper verifies the available literature on the nicotine, carbonyl compounds, nitrosamines, volatile organic compounds and metals content in aerosol generated from electronic cigarettes and compares it with these compounds content data in a cigarette smoke.

Keywords: electronic cigarette, aerosol, nicotine, toxic compounds, carbonyl compounds, metals, nitrosamines